Procedure Specific Tips
For optimum results and ease of use, follow the following tips.
Cataract Surgery
For optimum results and ease of use, follow the following tips.
OcuSeal is a polymer hydrogel. Once the polymerisation process is initiated.
i.e. when the powder and liquid components mix, the reaction cannot be
slowed or stopped. With this in mind the OcuSeal must be applied to the
desired area at
the end of the procedure in an uninterrupted fashion to avoid the hydrogel
polymerising in the applicator.
The polymerisation time of OcuSeal i.e. when the powder and liquid components
are mixed, is 30 seconds for complete gel formation. The optimal texture
for application to the ocular surface is a slightly more viscous liquid
therefore the surgeon may prefer to wait 5 seconds once the mixing has
taken place to get optimum ease of application.
If excess OcuSeal has been inadvertently applied to a greater area of
the ocular surface than required, the excess can be simply wiped away
while in a liquid form. Care must be taken when removing the excess once
the gel has formed, as the entire film of Ocuseal covering the desired
area may also be removed.
It is not entirely necessary to use the brush tip on the applicator. Many
surgeons prefer to wait until the OcuSeal becomes slightly viscous and
then merely drop the hydrogel over the desired surface.
It is ideal for the ocular surface to be as dry as possible before applying
OcuSeal.
Pterygium surgery.
Without a graft: OcuSeal is not an adhesive, it is a sealant.
For pterygium surgery without the use of a graft the surgeon must get
good wound approximation of
the conjunctiva first with a few “stay” or “anchor”
sutures and then apply a liberal amount of Ocuseal over the wound surface.
If this is not done, the conjunctiva
will pull apart. Ocuseal reduces the number of sutures needed is pterygium
surgery by 40%.
With a graft: Ocuseal has been used with great success with auto grafts
and amniotic grafts. The graft is secured in place with a few sutures
and OcuSeal is then placed over the graft. Poor results are attained when
the graft is placed over the Ocuseal.
LASIK surgery
OcuSeal provides a fast, cost effective and precise watertight seal of
the corneal flap to prevent epithelial ingrowth.
Histology
Histology Conclusions
• Biocompatible
• Cell migration/Tissue in-growth evident
• Capsule formation not evident
• Neo-Vascularization evident
• Degradation evident
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